What to do in Diablo 4 endgame after beating main campaign in Season 5

Stephanie Zucarelli
Diablo 4 endgame: Cultist Sacrifice

Diablo 4 has a lot more to offer than its main campaign, but players will only get to discover it after defeating Lilith for the first time. Blizzard have hidden many challenges that keep Sanctuary alive in the endgame, so Wanderers can explore these quests to keep building their characters.

Here’s everything you can do after beating the main campaign in Diablo 4 Season 5.

Change World Tiers in Season 5

Diablo 4 World Tiers
Tiers can be changed after completing Diablo 4’s main quest.

After completing the main story of Diablo 4, one of the first things you’ll be able to do is increase Sanctuary’s world level. In the endgame, players have access to two extra difficulty levels: World level 3- Nightmare (recommended for characters level 50 to 70) and World level 4 – Torment (recommended for characters level 70 and above).

Changing World Tiers offers the opportunity to face harder enemies but also gain loot of higher quality and rarity, such as Sacred and Ancestral items.

Complete all Nightmare Dungeons in D4

Diablo Nightmare Dungeon
Nightmare Dungeons can only be opened by its specific Sigil.

Once in World Level 3, Diablo 4 players will notice that Nightmare Sigils will start appearing on Sanctuary’s map. These sigils open Nightmare Dungeons, but they function as keys: players have no control over which will be activated. This mechanic will force Wanderers to stash every sigil in their inventory until they find which place they unlock, but they can be salvaged once used.

To get inside a Nightmare Dungeon, players will have to right-click a Nightmare Sigil in their inventory. This action will mark the place on the map, so it can be easier to find. At the end of these challenges, players will receive two pieces of loot and find an altar to upgrade Glyphs.

Boost your build with Paragon Board

Diablo 4 Paragon Board
Each Paragon Board has 6 different types of nodes.

Diablo 4’s Paragon Boards are custom passive trees, that can provide characters with stats to perfect their build. As players earn experience past level 50, they’ll also gain Paragon Points that can be spent on passive bonuses. Keep in mind that builds can only allocate up to 220 passives.

With the use of Glyphs, Wanderers will be able to improve Paragon Boards unlocking new abilities. Keep in mind that boards are designed according to each class and are tied to specific characters.

Challenge Diablo 4’s Helltides

Diablo 4 Helltide notification
Players will receive a notification when a Helltide event starts.

After finishing every Act of Diablo 4’s main story, players will have access to Helltide areas. These regions are where Hell’s influence makes enemies stronger and where players can search for crystals to unlock special reward caches.

Zones affected by a Helltide will spawn meteors as environmental hazards, increasing the monster level of the area by two above the player’s level. Defeating demons in this event will grant Aberrant Cinders that can be spent to open Tortured Chests that are scattered across the region affected by the Helltide.

After the Season 3 update, Helltides are now available at all times, with only a 5-minute intermission between them. Players will unlock these events in World Tier 3: Nightmare difficulty and will have to face the Helltide Commanders to gain precious loot.

Unlock new missions in the Tree of Whispers

The Tree of Whispers in Diablo 4
The Tree of Whisperers functions as a quest board.

Wanderers will encounter the Tree of Whisperers in Act 5 of the Diablo 4 campaign. It’s located in the northeast corner of Hawezar: there’s no way you can miss it, it’s the tree with the talking heads hanging from it.

When players are done with the main story, they’ll get a Priority Quest that will direct them to speak with the tree, who’ll ask to gather Grim Favors, which are gained after completing different missions. Keep in mind that every task rewards a different amount of favors:

  • Complete a dungeon: +5 Grim Favors.
  • Harvest a zone: +3 Grim Favors.
  • Clear a cellar: +1 Grim Favor.
  • Complete an event: +1 Grim Favor.
  • Kill an elite: +1 Grim Favor.
  • Slay an enemy type: +1 Grim Favor.
  • Finish a Ritual: +3 Grim Favors .
  • Defeat a World Boss: +5 Grim Favors.

The main goal is to earn 10 Grim Favors which can be exchanged for reward bundles.

Upgrade your Legendary Affixes in the Codex of Power

Diablo 4 New Codex of Power
Each Aspect can be unlocked after completing a dungeon.

The Codex of Power in Diablo 4 is a collection of Legendary Aspects and Affixes that you can imprint on your items. These enhancements can be used on Rare or Legendary items.

Even though Codex of Power is unlocked early in the main story, it might require Wanderers to keep playing after finishing it to get all Aspects. This can be done by completing every Dungeon in Diablo 4’s map.

Beat all World Bosses

Avarice, one of the World Bosses of Diablo 4
Every Diablo 4 season adds new World Bosses for players to put their builds to the test.

World Bosses are enormous demons that spawn across the map of Sanctuary. Players can encounter them at random during the main campaign. However, they’ll receive World Boss notifications in the endgame.

Diablo 4’s three main World Bosses are Ashava, The Pestilent; Avarice, The Gold Cursed and Wandering Death, Death Given Life. Each new season introduces new World Bosses for players to test their might, and they’ll need different materials to be summoned.

Here’s a list of every World Boss you can find during Season of the Infernal Hordes:

BossSeasonMaterials to summonTormented version
Uber Lilith1Complete the Fallen Temple Capstone in WT3.
Varshan12x Malignant Hearts
5x Malignant Hearts
15x Malignant Hearts
1x Stygian Stone
Duriel, King of Maggots22x Mucus-Slick Eggs
2x Shard of Agony
6x Shard of Agony
6x Mucus-Slick Egg
1x Stygian Stone
Grigoire, The Galvanic Saint22x Living Steel15x Living Steel
1x Stygian Stone
The Beast in the Ice29x Distilled Fear
1x Stygian Stone
27x Distilled Fear
1x Stygian Stone
Lord Zir29x Exquisite Blood27x Exquisite Blood
1x Stygian Stone
Tormented Malphas3N/A7x Igneous Cores
250x Shattered Stones
Andariel, Maiden of Anguish42x Pincushioned Dolls
2x Sandscorched Shackles
6x Sandscorched Shackles
6x Pincushioned Doll
1x Stygian Stone

Challenge The Gauntlet in Season 5

The Gauntlet is a fixed Dungeon available in the Season Realm that changes at the weekly reset. Introduced in Season 3, this Dungeon challenges players to kill as many demons and monsters as they can and get the top scores to compete for placement on the global Leaderboards.

Diablo 4 Horn of Trials
The Horn of Trials serves as the entry point to the Gauntlet.

Farm Uniques in The Pit

The Pit invites players to a timed, multi-level dungeon that increases in difficulty through various tiers. The goal in The Pit is to kill as many enemies as possible, along with a boss, within 15 minutes.

As you kill enemies, a progress bar fills up. Once the bar is full, a portal will appear, transporting players to a random boss that must be defeated before the timer expires to complete the run and earn the Mastery Bonus.

This endgame mode is one of the best options to farm Masterworking materials and Legendary and Unique items.

Artificer's Pit portal Diablo 4
The Pit’s difficulty scales depending on which World Tier you are on.

Diablo 4 Season 5 has introduced a complete rework of Unique Items and Legendary Aspects. You’ll also get a new set of quests to discover this season’s mechanics and two rogue-like endgame modes to put your build to the test.