Best ISO 45 loadout for Modern Warfare 2

Nathan Warby
ISO 45 SMG with Modern Warfare 2 logo

The ISO 45 is a great SMG choice for multiplayer in Modern Warfare 2. Before you take it for a spin, here’s the best ISO 45 loadout in Modern Warfare 2, along with the ideal attachments, Perks, and Equipment.

Modern Warfare 2 boasts a variety of weapons players can level up and use. When it comes to short ranges, SMGs are the ideal option to swiftly eliminate enemies, taking advantage of the high damage and mobility.

However, one weapon that is still very much relevant is the ISO 45 SMG, which is perfect for tight spaces and close-range fights thanks to its rapid-fire rate and high damage.

Here’s how to build the best ISO 45 loadout in Modern Warfare 2, including the recommended attachments, Perks, and Equipment.

Best Modern Warfare 2 ISO 45 loadout attachments

  • Barrel: 16″ XLB-S
  • Laser: 1MW Quick Fire Laser
  • Underbarrel: Merc Forgrip
  • Rear Grip: A30 Stout
  • Magazine: 45 Round Drum

Kicking off our best ISO 45 loadout for Modern Warfare 2 is the 16″ XLB-S barrel, which keeps the SMG’s shots suppressed and also buffs the range, bullet velocity, and recoil control. We’ve also gone for the A30 Stout rear grip for additional recoil control, allowing it to hold its own at mid-range.

Landing the first shot is essential in any fight, so we’ve picked the 1MW Quick Fire Laser to drastically cut down on ADS times. Then, we recommend the Merc Forgrip to improve hip-fire accuracy, ideal for frantic situations where there’s no time to ADS.

Finally, since the ISO 45 has a blistering fire rate, the 45 Round Drum will give you extra ammo to burn through before having to stop and reload.

ISO 45 SMG in Warzone 2
The ISO 45 is a great SMG in Modern Warfare 2.

Best Modern Warfare 2 ISO 45 Perks & Equipment

  • Base Perk 1: Bomb Squad
  • Base Perk 2: Scavenger
  • Bonus Perk: Fast Hands
  • Ultimate Perk: Ghost
  • Lethal Equipment: Semtex
  • Tactical Equipment: Flash Grenade
  • Field Upgrade: Dead Silence

Perks are essential to building the best ISO 45 loadout, and we’ve kicked things off with Bomb Squad to keep you protected from incoming explosives like Frag Grenades or Semtex. Scavenger will also prove useful as it lets you restock ammo from defeated enemies.

Even with Scavenger equipped, the ISO 45’s fire rate means you’ll be reloading often, so Fast Hands ensures you’re not out of the action for too long. Finally, Ghost is a must-have to keep you hidden from UAVs.

When it comes to Equipment, a Semtex is ideal for quickly clearing a room, while Flash Grenades disorientate players before you move in for the kill. Finally, Dead Silence will allow you to approach enemies and navigate the map without exposing the sound of your steps.

ISO 45 in MW2
The ISO 45 is deadly at close range.

How to unlock ISO 45 in Modern Warfare 2

Players can unlock the ISO 45 by either extracting the weapon from DMZ or completing an unlock challenge that requires players to get 45 Operator kills without taking any damage using SMGs.

Best Modern Warfare 2 ISO 45 alternatives

If the ISO 45 isn’t cutting it, try using another one of Modern Warfare 2’s great SMGs, such as the Lachmann Sub.

On the other hand, you could switch to an SMG hybrid like the Vaznev-9k, which excels at both close and mid-range.

For more on Modern Warfare 2, be sure to check out our other guides:

Best Modern Warfare 2 PC settings | Best Assault Rifles in Modern Warfare 2 |  Modern Warfare 2 Ranked Play rewards | Best Modern Warfare 2 controller settings | Best mouse & keyboard settings for Modern Warfare 2 | When is the next Modern Warfare 2 & Warzone 2 Double XP

About The Author

Nathan is a Senior Writer at CharlieIntel. He’s an expert in EA Sports FC, Call of Duty, and Overwatch, as well as superhero games, including Marvel’s Spider-Man. With a master's degree in Magazine Journalism from Nottingham Trent University, he worked as a Trainee Reporter for Derbyshire Live before moving into games media, with bylines at Dexerto, Cultured Vultures, and more. You can contact Nathan by email at [email protected].