All Diablo 4 Endgame boss Unique loot drop tables

Amitesh Dhar
Diablo 4 MalphasBlizzard

Taking on endgame bosses in Diablo 4 is one of the best ways to farm Unique items. To organize your grind and plan your builds, here’s a list of all Diablo 4 Endgame bosses and their Unique loot drop tables as of Season 3.

As you progress in Diablo 4, the quality of loot increases, and towards the endgame, having the best items and Aspects for your character is a must. And on top of the chain, there are Unique items with the best stats and buffs that are bound to improve your build which also explain their rarity.

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The endgame in Diablo 4 largely revolves around Nightmare Dungeons and bosses. As of Season 3, both the Eternal Realm and the Seasonal Realm feature five endgame bosses and they drop a specific set of Unique items when defeated.

To boost your progress and target farm Uniques, here’s a list of all Diablo 4 endgame bosses and their Unique loot tables.

All Diablo 4 endgame boss loot tables

It’s worth noting that while these bosses are available across both realms, you can summon and defeat them in World Tier 3: Nightmare, and World Tier 4: Torment only.

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Echo of Varshan

Varshan in Diablo 4Blizzard
The Echo of Varshan is a formidable foe.

How to summon: Collect different Malignant body parts (Gurgling Head, Trembling Hand, Malignant Heart, Blackened Femur.)

You can collect the parts above from the Tree of Wishpers caches. Once you’ve collected all the items, head into the Malignant Burrow below the Tree of Whispers to summon this boss. Once you defeat it, you can claim the following Unique rewards:

SorcererTal Rasha’s Iridescent Loop, Staff of Endless Rage, Esu’s Heirloom, Raiment of the Infinite
DruidAiridah’s Inexorable Will, Mad Wolf’s Glee, Vasily’s Prayer, Greatstaff of the Crone
BarbarianRing of Red Furor, Fields of Crimson, 100,000 Steps, Gohr’s Devastating Grips
NecromancerRing of the Sacrilegious Soul, Bloodless Scream, Deathless Visage, Deathspeaker’s Pendant
RogueWrithing Band of Trickery, Condemnation, Eyes in the Dark, Skyhunter
All classesFrostburn, Mother’s Embrace

Grigoire, the Galvanic Saint

Grigoire Diablo 4Blizzard
Grigoire, the Galvanic Saint can drop certain Uniques like the Hunter’s Zenith.

How to summon: Collect Living Steel from Helltides

Once you’ve collected enough Living Steel, make your way to the Hall of the Pentinent dungeon in Dry Steppes. You’ll need two Living Steel to summon him in World Tier 3, and five Living Steel to summon him in World Tier 4 in Diablo 4. You can check out the Uniques for Grigoire in the following table:

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SorcererStaff of Lam Esen, Iceheart Brais, Gloves of the Illuminator
DruidInsatiable Fury, Hunter’s Zenith, Waxing Gibbous, The Butcher’s Cleaver
BarbarianRamaladni’s Magnum Opus, Rage of Harrogath, Ancients’ Oath, Battle Trance, The Butcher’s Cleaver
NecromancerBlood Artisan’s Cuirass, Howl from Below, Greaves of the Empty Tomb
RogueWord of Hakan, Grasp of Shadow, Windforce
All classesPenitent Greaves

Lord Zir

Lord Zir in Diablo 4Blizzard
Lord Zir is one of the most difficult bosses in Diablo 4.

How to summon: Collect Exquisite Blood from Legion Events.

Although he was the boss in the past Season of Blood, you will still be able to summon him in the game. Head to The Ancient Seat in Fractured Peaks to summon Zir, and check out the Uniques that he drops when defeated:

SorcererStaff of Endless Rage, Iceheart Brais, Raiment of the Infinite, Esadora’s Overflowing Cameo
DruidMad Wolf’s Glee, Vasily’s Prayer, Greatstaff of the Crone, Fleshrender, The Butcher’s Cleaver
BarbarianRamaladni’s Magnus Opus, Rage of Harrogath, Gohr’s Devastating Grips, Overkill, The Butcher’s Cleaver
NecromancerBlood Artisan’s Cuirass, Deathless Visage, Greaves of the Empty Tomb, Lidless Wall
RogueGrasp of Shadow, Eyes in the Dark, Skyhunter, Asheara’s Khanjar
All classesPenitent Greaves, Razorplate, Temerity

The Beast in Ice

Diablo 4 Season 2 Beast in IceBlizzard
Beast in Ice is an extremely formidable enemy in the game.

How to summon: Collect Distilled Fear by completing Tier 30 Nightmare Dungeons.

Once you’ve collected enough Distilled Fear, make your way to the Occultist in Diablo 4 to craft the Glacial Fissure Nightmare Sigil. Here are the Uniques that you can get by defeating The Beast in Ice boss in Diablo 4:

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SorcererStaff of Lam Esen, Esu’s Heirloom, Gloves of the Illuminator, The Oculus, Starfall Coronet
DruidInsatiable Fury, Hunter’s Zenith, Waxing Gibbous, Storm’s Companion, Unsung Ascetic’s Wraps
BarbarianFields of Crimson, 100,000 Steps, Ancients’ Oath, Battle Trance, Hellhammer, Ring of the Ravenous
NecromancerBloodless Scream, Howl from Below, Deathspeaker’s Pendant, Ring of Mendeln, Mutilator Plate
RogueCondemnation, Word of Hakan, Windforce, Eaglehorn, Beastfall Boots
All classesFrostburn, Mother’s Embrace, Fists of Fate, Tassets of Dawning Sky, Paingorger’s Gauntlets

Duriel, King of Maggots

Echo of Duriel Diablo 4 Season 2Blizzard
You can get Tibault’s Will by defeating Duriel.

How to summon: Collect Mucus-Slick Eggs and Shards of Agony by defeating Varshan and Grigoire respectively.

It’s worth remembering that the Mucus-Slick Eggs are only available in World Tier 4. So once you’ve collected the two items, you need to make your way to the Gaping Crevasse dungeon and find the altar to summon Duriel.

Duriel is the only boss in the game that drops Uber Uniques, so you should farm the fight whenever you can.

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SorcererFlamescar, Blue Rose
DruidTempest Roar, Dolmen Stone
BarbarianAzurewrath, Tuskhelm of Joritz the Mighty
NecromancerBlack River, Blood Moon Breeches
RogueCowl of the Nameless, Scoundrel’s Leathers
All classesGodslayer Crown, Flickerstep, Tibault’s Will, X’Fal’s Corroded Signet, Soulbrand, Banished Lord’s Talisman
Uber UniquesDoombringer (Barbarian, Necromancer, Rogue), The Grandfather (Barbarian, Necromancer), Melted Heart of Selig, Andariel’s Visage, Harlequin Crest, Ring of Starless Skies, Abavarion, Spear of Lycander (Druid, Sorcerer)

For more on Diablo 4, be sure to check out the rest of our content:

Best Diablo 4 Druid builds | Best Diablo 4 Barbarian build | Diablo 4 skill tree builder | Is Diablo 4 coming to Nintendo Switch | How to fast travel in Diablo 4 | Is Diablo 4 playable on the Steam Deck | How to salvage gear in Diablo 4 | How to transmog gear in Diablo 4 | Diablo 4 Ashava boss guide | Diablo 4 server status

About The Author

Amitesh is a writer at CharlieINTEL. When not writing about video games, you'll find him immersed in either Destiny 2 or Diablo 4, trying to perfect builds for different activities. You can get in touch with him at [email protected]